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What’s this project about?
Each year, around 1.4 million people worldwide are diagnosed with lung cancer, and unfortunately survival rates are very poor. We urgently need to find more effective treatments to improve the outcome for people with this disease. Dr Corinne Faivre-Finn is leading a major international clinical trial that aims to find the best treatment for small cell lung cancer (SCLC).
What is the science behind this project?
People with SCLC often have a combination of chemotherapy and radiotherapy. But currently, they can receive this in different treatment schedules. For example, some will have both treatments at the same time, whereas others receive one after the other. Equally, some people have radiotherapy twice a day, while others have it only once a day. Unfortunately, it's not clear at the moment which is the most effective way to treat people with SCLC. This is where the clinical trial comes in.
The CONVERT trial, as it is called, aims to discover the most effective chemotherapy and radiotherapy schedule for people with SCLC. The researchers will investigate the best total dose of radiation to give, and whether radiotherapy once or twice a day provides the greater benefits.
Looking to the future
The trial started in early 2008 and the team aims to recruit more than 500 people with SCLC over the next four years.
The researchers hope the trial will show which treatment schedule is the best at prolonging life and minimising side effects for patients. The one that provides the greater benefits may be adopted as the new ‘gold standard’ treatment for SCLC in the future - improving the outlook and quality of life for people with this common form of cancer.
For more information about lung cancer you can visit our CancerHelp UK website lung cancer pages. You can find out more about this trial on our CancerHelp UK clinical trials database.
The difference you can make
Lung cancer is the most common cancer in the world and there is an urgent need to find more effective treatments. Dr Faivre-Finn’s trial will help beat lung cancer in the future.
Please help us raise £71,000 to help fund one year of Dr. Faivre-Finn’s vital 4 year trial.
Project update
The trial has now recruited 21 patients at twelve different sites across the UK and Belgium. Over 90 other sites have expressed an interest in taking part too.
You can read more about the CONVERT trial here.
Donate now and you can help improve the outlook and quality of life for people with small cell lung cancer.





