Project Brazil 2012 - Bobby Moore Fund

Last updated: 10/08/2012

Professor DunlopWhat is this project about?

This project is raising money for research that will help to identify people genetically most likely to be at risk from bowel cancer thereby enabling them to receive early and regular screenings for the disease.

The research is carried out by Professor Malcolm Dunlop at the Medical Research Council’s Human Genetics Unit in Edinburgh who is using cutting edge technology to uncover the genes associated with bowel cancer.

Fundraising for this research project is being undertaken by participants of the 2012 Bobby Moore Fund International Project to Brazil. Through Project Brazil, vital money will be raised to tackle bowel cancer in the UK and work will be carried out to improve young lives abroad. 

 
 
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Why support this project?

Bowel cancer is the third most common cancer in the UK. In 2008, almost 40,000 people were diagnosed with the disease. However, the good news is that five-year survival rates have doubled over the last 40 years meaning that over half of the people diagnosed with bowel cancer will survive their disease for at least ten years. But we have a long way to go with around 16,000 people still dying from bowel cancer every year in the UK.

Professor Malcolm Dunlop’s work to uncover the genes associated with bowel cancer will make it easier for doctors to identify and put forward those people with a higher risk of the disease for regular screening. This will help to improve survival rates by ensuring that the disease is diagnosed and treated at an earlier stage.


What’s the science behind this project?

Although there are lots of lifestyle choices that can affect the risk of developing bowel cancer, such as alcohol, being overweight and smoking, scientists also know that some people get the disease because they inherit faulty genes that make them more likely to develop it.

Professor Dunlop and his team have already made great progress in identifying new gene faults or variations that are associated with an increased risk of bowel cancer.

In this project, the researchers will try to understand more about the genes and mechanisms we already know about, and search for new ones that have not yet been found.

Read more about the science>

Professor Dunlop and his team will look at lots of genetic data that they have previously collected from people with bowel cancer and compare them with samples from healthy people to see the differences. They will go on to study what these differing genes do and how alterations or ‘faults’ in these genes lead to cancer.

As well as finding out genetic factors that increase risk of bowel cancer, the researchers will also look for genes that can influence the chances of survival in someone who has been diagnosed with bowel cancer. Knowing the genetic makeup of someone who is likely to survive the disease could help doctors predict which people are likely to respond well to treatment.

This work will move the researchers towards having a more complete picture of the genes which influence why bowel cancer develops and will hopefully reveal targets for new treatments. The findings may also help doctors to predict which people are most likely to get the disease, so they can refer them for screening to ensure bowel cancer is detected as early as possible.

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What is the Project Brazil 2012 international event?

Volunteers painting the school wallsIn addition to raising funds to tackle bowel cancer in the UK, the Bobby Moore Fund supports international projects that help to improve young lives abroad.

The Project Brazil 2012 event was set up in response to the collapse of an entire school building in Chapada Dos Veadeiros National Park in Brazil in 2008. This subsequently resulted in half the pupils being educated in a local rundown farmer’s house, with the remainder travelling 28km each way by dirt road to the nearest town.

In September 2012, a group of Bobby Moore Fund volunteers will travel out to fully renovate the school – vastly improving the lives of young people and the community who have been affected.

Read more about Project Brazil>

The Bobby Moore Fund will work in partnership with the local community to build a new school with two classrooms, a kitchen and a bathroom which will serve 66 students.  Volunteers will work hard to carry out tasks such as:

  • laying the flooring
  • plastering and painting the walls
  • painting the exterior of the new building
  • fixing the door and windows.

"I have taken part in several of our International Projects and found them to be some of the most rewarding experiences of my life. The help that is being given in these remote areas is of real benefit to the local communities and the money raised through the participants' fantastic fundraising efforts is hugely important to the work of the Bobby Moore Fund. To know that you are making a real difference to both causes is something very special.”  Stephanie Moore MBE

Please support this project and help make a difference to the lives of bowel cancer patients in the UK as well as an isolated Brazilian community.

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About the Bobby Moore Fund


The Bobby Moore Fund was set up by Stephanie Moore MBE in partnership with Cancer Research UK in 1993. Stephanie established the Fund following the death of her husband, legendary footballer Bobby Moore OBE who died from bowel cancer aged just 51. 

The Bobby Moore Fund raises money for research into bowel cancer and works to increase public awareness of the disease.  Since 1993, over £17 million has been raised for dedicated bowel cancer research.


How can you help?

Bobby Moore Fund logo

Your support will help us continue our work to find better ways to prevent, diagnose and treat bowel cancer. If we can find new ways to identify the people most at risk, we will be able to monitor them more closely, and treat them at an earlier stage if necessary. Ultimately all this work could help us prevent more cases of bowel cancer and save the lives of people with the disease.